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Infinity PhII results a blow for PI3K in inflammation

 
• By Eleanor Malone

Infinity Pharmaceuticals has discontinued development of its oral PI3K inhibitor duvelisib in rheumatoid arthritis after the candidate failed in a Phase II trial.

Infinity Pharmaceuticals has discontinued development of its oral PI3K inhibitor duvelisib in rheumatoid arthritis after the candidate failed in a Phase II trial.

The product was the most advanced in its class for inflammatory conditions across industry. It inhibits Class I phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma. PI3Ks are involved in multiple cellular processes including...

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