Infinity PhII results a blow for PI3K in inflammation

Infinity Pharmaceuticals has discontinued development of its oral PI3K inhibitor duvelisib in rheumatoid arthritis after the candidate failed in a Phase II trial.

Infinity Pharmaceuticals has discontinued development of its oral PI3K inhibitor duvelisib in rheumatoid arthritis after the candidate failed in a Phase II trial.

The product was the most advanced in its class for inflammatory conditions across industry. It inhibits Class I phosphoinositide-3-kinase (PI3K)-delta...

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