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Merck's Keytruda Wins NSCLC Edge Over BMS' Opdivo

 
• By Francesca Bruce

NICE has changed its mind and provisionally recommended Merck's Keytruda for non-small-cell lung cancer thanks to a discount. The news means Merck could gain an edge over rival drug Opdivo from BMS, which has so far had less success with NICE.

New draft guidance from NICE, the health technology appraisal institute for England and Wales, recommends Merck & Co. Inc.'s PD-1 inhibitor Keytruda (pembrolizumab) for some non-small cell lung cancer patients. The news could put Keytruda ahead of its rival and fellow PD-1 inhibitor from Bristol-Myers Squibb Co.'s, Opdivo (nivolumab), which has so far failed to secure a positive recommendation from the institute.

NICE is now recommending Keytruda for treating locally advanced or metastatic PD-L1-positive non-small-cell lung cancer in adults who have had...

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