Sanofi and Regeneron Pharmaceuticals Inc. are looking to break into the crowded rheumatoid arthritis market by establishing a compelling value proposition for the interleukin-6 receptor blocker Kevzara (sarilumab). The wholesale acquisition cost of Kevzara is set at $39,000 per year for both the 200 mg and 150 mg doses, a price that is 30% lower than the two market-leading tumor necrosis factor inhibitors, AbbVie Inc.'s Humira (adalimumab) and Amgen Inc.'s Enbrel (etanercept).
Kevzara also could undercut Roche's entrenched IL-6 inhibitor Actemra (tocilizumab), depending on the dosing that is used, although not as substantially