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Celgene Further Commits To Neuroscience With Prothena Pact

 
• By Kevin Grogan

It is a risky business but the biotech major is paying $150m upfront, and potentially hundreds of millions of dollars more, to work with Prothena and develop therapies targeted at proteins implicated in highly challenging neurodegenerative diseases such as Alzheimer's and ALS.

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Celgene and Prothena team up to tackle neurodegeneration • Source: Shutterstock

Celgene Corp. has taken its cheque book out to sign a second neurodegenerative disease pact this month, paying $100m upfront and a $50m equity investment to team up with Prothena Corp. PLC and develop therapies to tackle conditions such as Alzheimer's and amyotrophic lateral sclerosis.

The multi-targeted collaboration will focus on three proteins implicated in neurodegenerative diseases. The first target is tau in Alzheimer's, progressive...

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