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Filgotinib Shaping Up To Be Success Story For Gilead and Galapagos

 
• By Kevin Grogan

Impressive Phase II data for Gilead and Galapagos’ filgotinib in psoriatic arthritis and progress into Phase III for ulcerative colitis suggest that the investigational JAK inhibitor could potentially become a market leader in the class for these and other inflammatory indications.

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Filgotinib climbing up the clinical ladder • Source: Shutterstock

Gilead Sciences Inc.'s and Galapagos NV's view that filgotinib has considerable potential as a treatment for range of inflammatory diseases has been supported by more clinical progress for the oral Janus kinase (JAK) inhibitor, this time in psoriatic arthritis (PsA) and ulcerative colitis (UC).

First up, the firms unveiled data from the Phase II EQUATOR study which showed filgotinib achieved its primary endpoint of...

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