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Lilly Puts Down $200m To Use Dicerna's RNAi Platform For Metabolic, Neurological Diseases

 
• By Mandy Jackson

Dicerna CEO tells Scrip the companies talked for two years and the collaboration came together as new Lilly R&D leadership looked to add novel approaches. Milestone fees of $350m per target for 10 or more targets value the deal at $3.7bn.

businessman and businesswoman are shaking hands and exchanging folder after agreement was reached

Dicerna Pharmaceuticals Inc. went on the hunt for partners after refocusing its research and development efforts on its GalXC platform and soon began talking with Eli Lilly & Co. about harnessing the RNAi technology in the big pharma's areas of expertise. Now, the companies have entered into a formal collaboration agreement worth $200m up front and $3.5bn or more in milestone fees.

Cambridge, Mass.-based Dicerna and Lilly announced on Oct. 29 that they will use the GalXC platform to discover, develop and commercialize RNA interference (RNAi) medicines for cardio-metabolic disease, neurodegeneration and pain

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