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Sunovion’s TAAR1 Agonist Brings Something New To CNS Arena

‘Exciting Step Forward’?

 
• By Ian Haydock

Sunovion’s new schizophrenia candidate is generating investor attention given its first-in-class mode of action. Newly published clinical results appear to bear out its promise in a sector where there’s been limited innovation.

Schizophrenia
New Hope In Schizophrenia? • Source: Shutterstock

One of the main points of focus for analysts at an R&D briefing by Sumitomo Dainippon Pharma Co. Ltd. (SDP) in Japan last month was an innovative molecule for schizophrenia developed by the Japanese firm’s US affiliate Sunovion Pharmaceuticals Inc. and now moving through late pivotal trials.

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• By Andrew McConaghie

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Roche’s Brain Shuttle Delivers In Alzheimer’s, Moves Ahead To Phase III

 
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Axsome Plans Excessive Sleepiness Study In Depression After Phase III Failure

 
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The study’s failure in the overall MDD population was not a surprise, but solriamfetol’s efficacy in MDD with EDS provided a rationale for testing it in that subpopulation.

Cerevance To Focus On Parkinson’s Adjunctive Therapy After Phase II Miss

 
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After failing a Phase II monotherapy study in early Parkinson’s, Cerevance will focus on adjunctive therapy without abandoning the monotherapy concept.

More from Therapy Areas

Ironwood To Consider All Options With Apraglutide Setback In SBS

 
• By Joseph Haas

With the FDA asking for another Phase III trial, the short bowel syndrome drug apraglutide could be years away from market, while the Linzess patent expiry and near-term debt loom.

Pfizer’s Danuglipron Is Done, Sparking M&A Speculation

 
• By Jessica Merrill

The company discontinued development of its oral GLP-1 receptor agonist for weight management due to a safety signal.

Amgen’s Imdelltra Sets The Pace In Small-Cell Lung Cancer

 
• By Andrew McConaghie

The bispecific is the first in its class to record a Phase III survival win in small-cell lung cancer, although antibody-drug conjugates and other rivals could challenge in the coming years.