Novartis Teams Up With Sangamo In Brain Gene Therapy Pact

Autism At The Center of Collaboration

Novartis is the latest big pharma to sign up for access to Sangamo's gene therapy technologies, inking a deal that will focus on neurodevelopment disorders and could be worth in the region of $800m.

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Tackling brain disorders with gene therapies • Source: Shutterstock

Novartis AG is paying $75m upfront to use Sangamo Therapeutics, Inc.'s zinc finger technology platform and develop genomic medicines for autism, a long-time area of interest for the Swiss major, and other neurodevelopmental disorders.

The three-year collaboration will see Novartis get exclusive rights to Sangamo's zinc finger protein transcription factors (ZFP-TFs) targeted to three undisclosed genes which are associated with neurodevelopmental disorders, including autism spectrum disorder and intellectual disability

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