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Novartis Excited About Iptacopan But Downcast After Huntington’s Blow

Branaplam Development Halted

 
• By Kevin Grogan

The Swiss major is close to its first submission for ‘pipeline in a pill’ iptacopan but has conceded defeat with branaplam as a potential treatment for Huntington’s disease.

Novartis HQ
• Source: Novartis

Novartis AG's pipeline update during its fourth-quarter results presentations was a mixed bag, with the company's enthusiasm for iptacopan tempered by the disappointing news that it has terminated development of branaplam for Huntington’s disease.

Hopes were high a couple of years ago when Novartis announced that after working on branaplam for over five years for type 1 spinal muscular atrophy (SMA), it was switching...

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