Acepodia Plays Dual-Payload Ace To Join Global ADC Race

Acepodia’s dual-payload antibody-drug conjugates can link multiple tumor-killing agents without antibody modification. Apart from a GPC3-targeting candidate, the Taiwan-US biotech is also working on a bispecific antibody ADC with two different payloads, its CEO tells Scrip in an interview.

Two,Darts
Acepodia's dual-payload design is believed likely to overcome malignant tumors’ resistance to single-payload ADCs and thus improve survival benefits including overall survival. (Shutterstock)

Acepodia is emerging as one of the world’s few developers of antibody-drug conjugates (ADCs) preparing to advance into the clinic with a dual payload-fixed design of targeted cancer therapy.

Key Takeaways
  • Acepodia is progressing dual-payload antibody-drug conjugates into the clinic based on its proprietary Antibody-Dual-Drugs Conjugation platform, which aims to improve efficacy over existing single-payload ADCs.

Based out of Taipei, Taiwan and Alameda, CA in the US, the small bioventure is pinning high hopes on its proprietary Antibody-Dual-Drugs Conjugation (AD2C) platform to elevate its still preclinical...

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