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Clinical Trials

Deals In Depth: December 2024

Nine $1bn+ alliances were penned in December, and two exceeded $2bn.

Teva Plots Out 2026 Launch For ‘Night And Day’ Olanzapine Long-Acting Injectable

At the J.P. Morgan Healthcare Conference in San Francisco, Teva has provided a timeline for its much-talked-about long-acting injectable olanzapine candidate, after wrapping up a Phase III clinical trial with data that the firm believes will give it a major advantage over its competitors.

Global Regulator Action To Improve Diversity In Clinical Trials

As efforts to improve diversity in clinical trials gain momentum globally, regulators in the UK, the EU, Canada, Australia and Japan were asked about their efforts to support representative enrolment. 

Ovid’s Gameplan: Flicking The Master Switch In Neurology

One month after announcing a pipeline pivot, Ovid Therapeutics talked to In Vivo about the importance of making strategic decisions with discipline, and the imminent neurology revolution.

Chinese Firms Expand Solo Global Phase III Activity Including US Sites

Throughout 2024, Chinese firms as sole sponsors initiated a total of seven global Phase III trials that including US sites. BeiGene, Genfleet and InnoCare are expected to add four similar studies this year.

Oculis Eyes Opportunities For Third Ophthalmology Candidate

The Swiss-headquartered, NASDAQ-listed group has posted a Phase II win for OCS-05 in acute optic neuritis, which opens up its potential in additional, and much larger, neuro-ophthalmic indications, CEO Riad Sherif tells Scrip.

Medtech 2025 Expert AI Predictions: ‘Biggest Leap Leveraging AI In Oncology,’ Says Verily’s Andrew Trister; Multimodal Integration, Use Of AI Agents

Medtech Insight asked three leading AI experts, Verily’s Andrew Trister, Ferrum Health’s Pelu Tran and Hologic’s Jennifer Schneiders, to offer their perspectives on the future of AI in health care.

CARsgen Claims First Clinical Win For CLDN 18.2 CAR-T In G/GEJ Adenocarcinoma

CARsgen's anti-Claudin 18.2 CAR-T therapy satricabtagene autoleucel has met its endpoint in a pivotal Phase II trial in later-stage gastric/gastroesophageal junction adenocarcinoma, paving the way for a China NDA filing.

Boosting Reliability: EMA Backs AI Tool For MASH Trials

An artificial intelligence-based pathology tool for metabolic dysfunction-associated steatohepatitis shows promise for a drug development landscape that is said to be “fraught with trials that have shown borderline results or outright failures based on liver histology.”

AI In Biopharma: Distinguishing Correlation From Causation

The ability of artificial intelligence tools to distinguish correlation from causation could prove to be a boon to the industry.