US Study Lends Support To Polypill Proposals

Fixed-dose polypills containing commonly available generic cardiovascular agents could cut risks in low-income populations within the US, a randomized clinical trial suggests.

Mobile
A US study conducted in Mobile, Alabama, supports suggestions that a four-drug polypill could reduce cardiovascular risk • Source: Shutterstock

Giving patients fixed-dose ‘polypills’ combining four commonly available generic drugs could reduce the rates of cardiovascular disease among people with “low socioeconomic status” and “non-white persons” in the US, suggest the results of a randomized trial reported in the New England Journal of Medicine.

Publication of the findings from the US polypill study conducted in just over 300 adults in Alabama comes shortly after The Lancet journal carried a report on a large-scale Iranian...

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