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Roche: US Biosimilar Impact Worse Than Expected And ‘Pretty Much Like Europe’

Avastin EU Biosimilars Marked Complete Level Of Competition

 
• By Dean Rudge

Roche was forced to revise its forecasts for biosimilar competition last year, but even an upward revision of CHF1bn fell short as biosimilar sponsors stole a march in the US at a level that caught the originator by surprise.

Roche
Roche had hoped erosion in the US would "be a little slower." • Source: Shutterstock

Roche has expressed surprise at the level of penetration last year in the US for long-heralded biosimilar versions of Avastin (bevacizumab), MabThera/Rituxan (rituximab) and Herceptin (trastuzumab), as full-year financial figures revealed the global impact of biosimilars was higher even than the originator’s recently revised estimates.

In 2020, biosimilar competition to the three oncology blockbusters led relative sales in the US, Europe and Japan to plunge by CHF5.1bn ($5.7bn); worldwide, the impact was approximately CHF5

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