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180 Life Sciences Adalimumab Study Publishes Positive IIb Dupuytren’s Disease Data

Company Has Started Initial Consultations With US And UK Regulators

 
• By Chloe Kent

Adalimumab could find itself with a tenth official indication, after 180 Life Sciences found that it was able to effectively treat nodule hardness and size in Dupuytren’s disease during a phase IIb study.

Hands of a patient with Dupuytren's disease
Dupuytren's disease currently has few treatment options. • Source: Shutterstock

A phase IIb study of adalimumab to treat patients with Dupuytren’s disease has delivered positive data, suggesting that a local injection of the drug in the early stages of fibrosis could have a profound biological effect and provide a much-needed therapeutic option for patients.

180 Life Sciences, which carried out the research in collaboration with the University of Oxford, has now begun consultations with US and UK regulatory authorities to determine pathways to potential...

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