Unpicking The CMS Guide On Price Negotiation: A Dive Into The US Eylea Biosimilar Landscape

Confusion And Questions For Industry As Regeneron Plots 8mg Eylea Dosage

Generics Bulletin looks at the implications and takeaways for biosimilar sponsors following the recent publication of long-awaited CMS guidance on price negotiation under the Inflation Reduction Act.

Joe Biden, Democratic Party (Ron Adar/Shutterstock.com)
The IRA is landmark new law signed by the Biden administration • Source: Shutterstock

With its benchmark status among ophthalmologists to treat forms of macular degeneration and multi-billion-dollar annual sales, Regeneron’s Eylea (aflibercept) represents one of the most lucrative potential US opportunities for biosimilar sponsors in the middle of this decade.

A swathe of firms is working franticly to be among the first wave, following biosimilar inroads last year into the...

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