Tanvex Takes A Hit On Trastuzumab With CRL In US

Filing For Herceptin Biosimilar Is Knocked Back By FDA

Tanvex has seen its application for a trastuzumab biosimilar knocked back by the US Food and Drug Administration, receiving a complete response letter over the filing.

Tanvex has received a CRL for trastuzumab (Shutterstock)

Tanvex has received disappointing news on its US filing for a Herceptin (trastuzumab) biosimilar, with the US Food and Drug Administration issuing the firm with a complete response letter over its TX05 trastuzumab candidate.

The Taiwanese firm said the CRL for the breast cancer and gastric cancer treatment “cites certain issues to be addressed by the downstream manufacturer of TX05, which is a third-party service provider of Tanvex US for its drug product,” adding that “Tanvex US is proactively discussing with

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