Pfizer’s recent determination to pay $43bn for antibody-drug conjugate (ADC) pioneer Seagen, the largest pharmaceutical deal since AbbVie’s $63bn takeover of Allergan three years ago, stems in part from the remote chance that a biosimilar sponsor would ever be motivated or indeed able to replicate the groundbreaking medicines.
Biosimilar Antibody-Drug Conjugates? Pfizer Isn’t Banking On It
‘The Regulatory Path Has To Be Determined. It Doesn’t Exist Today’
Pfizer’s $43bn agreement to acquire Seagen would layer its portfolio and pipeline with vastly complex antibody-drug conjugates – a class of drug that both parties feel might be almost immune to biosimilar competition.

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Bringing in sales that translated to nearly $1.5bn last year, Japan’s Towa was feeling upbeat after a challenging few years, both for itself and the broader Japanese generics market. However, its financial guide for the next 12 months has left investors feeling cold.
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