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Synosis: the Financial Leverage of Translational Medicine

 
• By Roger Longman

Biotech investors have struggled with the fact that it takes take years, hundreds of millions of dollars, and widely varying sets of expertise to create a product. For Synosis, the answer is translational medicine: it starts life with nine compounds from three European companies, aiming to figure out the best indications and dosing for each, prove them through Phase II, and then out-license them.

For decades, venture investors have struggled with the a basic business-model problem: how to make money from companies that, to create a product, require years, hundreds of millions of dollars, widely varied kinds of management expertise, and lucky sevens on dozens of scientific and commercial bets.

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