Immuno-oncology firm Advantagene Inc. raised $14.2m through the sale of its Series A convertible preferred shares to undisclosed investors. National Securities Corp. was the placement agent. (Sept.)
Advantagene is developing cancer treatments based on its GMCI (Gene Mediated Cytotoxic Immunotherapy) platform, which is a viral vector technology based on the aglatimagene besadenovec (AdV-tk) gene vector specially engineered to deliver the herpes simplex-derived thymidase kinase gene to target cells. Administration of GMCI candidates consists of an injection at the tumor site (to deliver the AdV-tk) and an oral dose of an activating prodrug, which together causes a cytotoxic reaction at the tumor site and induces a patient-specific immune response