Editas Deal Opens Allergan's Eyes To CRISPR Opportunities

Editas' stock shot up 11% by mid-morning on March 14, after the gene therapy company announced a deal with Allergan worth $90m up front for "cool" CRISPR programs in ocular indications. However, the lead therapy included in the deal offers potentially limited profitability in a small orphan space.

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Allergan makes its first move into CRISPR gene editing via Editas deal • Source: Horizon Discovery

Allergan PLC has entered a strategic alliance with Editas Medicine Inc. for exclusive access and the option to license up to five of the latter firm's genome-editing ophthalmic programs – including its lead program for Leber congenital amaurosis (LCA), a rare, inherited retinal degenerative disease that appears in childhood and leads to blindness. This lead therapy is due to enter Phase I trials later in 2017.

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