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Amgen Hit By Enbrel 'Peculiarities' And Repatha Resistance

 
• By Mandy Jackson

Amgen reported a surprising double-digit decline for Enbrel during the first quarter and sales for the cholesterol-lowering biologic Repatha showed that the PCSK9 inhibitor is not going to make up for the company's declining revenue any time soon – at least not while payers continue to block its use.

Arrows miss target

Amgen Inc.'s PCSK9 inhibitor Repatha (evolocumab) remains a long way off from driving the kind of revenue growth that the company needs to make up for declining sales of its legacy blockbuster products, including an unexpected 15% drop for Enbrel (etanercept) in the first quarter.

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