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Novo's Tresiba Significantly Reduces Hypoglycemia Versus Lantus In DEVOTE

 
• By Kevin Shannon

Novo Nordisk's Tresiba reduced the risk of severe hypoglycemia in type 2 diabetes by 40% compared to Sanofi's standard-of-care insulin Lantus. The data may convince physicians to prescribe longer acting insulins, but their effect on formulary positioning remains to be seen.

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Novo Nordisk AS's Tresiba (insulin degludec) was shown to reduce the risk of severe hypoglycemia in type 2 diabetes by 40% compared to the standard of care, Sanofi's Lantus (insulin glargine), in the DEVOTE cardiovascular outcomes trial – a significant achievement given the high prevalence of hypoglycemia and the severe threat it poses to this population.

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