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Celgene IBD Pipeline In Question As Mongersen Crohn’s Disease Trial Ends

 
• By Sten Stovall

Celgene will stop late-stage testing of its investigative therapy mongersen for Crohn’s disease after a data monitoring committee said it would be futile to continue.

Crohn's disease
Celgene Stopped A Phase III Trial For Mongersen In Crohn's Disease • Source: Shutterstock

Celgene Corp.'s hope of becoming an inflammation and immunology leader is being threatened as it pulls the plug on two studies evaluating mongersen for the treatment Crohn's disease at the recommendation of the trial's independent data monitoring committee.

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• By Dexter Jie Yan

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In Brief: BriaCell’s Breast Cancer Cell Therapy Boosts Survival In Phase II

 
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In Brief: BriaCell’s Breast Cancer Cell Therapy Boosts Survival In Phase II

 
• By Sushmita Panda

BriaCell announced its cell therapy Bria-IMT plus checkpoint inhibitors bested Gilead’s Trodelvy in a Phase II trial in HR+ breast cancer; a Phase III trial is enrolling.

China’s Biotech Stocks Proved More Resilient Than US’s Amid Market Turmoil

 
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Henlius In David Versus Goliath Race With Pfizer For First PD-L1 ADC

 
• By Dexter Jie Yan

While Henlius Biotech’s PD-L1-targeting antibody-drug conjugate HLX43 is struggling to catch up with Pfizer’s PF-08046054, the global frontrunner in the space, a key differentiation of the China-originated asset could lie in PD-L1-negative patients.