Auris Medical's Second Phase III Tinnitus Trial Disappoints

Auris Medical Holding's investigational tinnitus product, Keyzilen, has failed to meet its primary efficacy endpoint in an interim analysis of a second Phase III trial, adding to a series of clinical disappointments over the past few years for the Swiss biotech.  

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A second Phase III study of Auris Medical Holding AG's investigational product, Keyzilen (esketamine, AM-101), has failed to improve acute inner ear tinnitus in a top-line interim analysis, adding to other negative trial results reported by the neurotology specialty company.

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