AbbVie Inc. claimed an important win on April 9 when it reported positive efficacy and safety in rheumatoid arthritis for its JAK1 inhibitor upadacitinib in the drug's largest and longest Phase III clinical trial to date, including a lack of cardiovascular events that raised red flags in other late-stage studies.
AbbVie's Upadacitinib Safety Appears Improved In Largest, Longest RA Study
AbbVie's JAK1 inhibitor upadacitinib bested the company's blockbuster Humira in the largest and longest trial to date – on both efficacy and safety – perhaps alleviating concerns about cardiovascular events.
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