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Nabriva On Pace For Lefamulin NDA; Stock Tumbles Despite Trial Success

 
• By Joseph Haas

With a pair of Phase III trials demonstrating lefamulin’s non-inferiority to moxifloxacin in CABP, Nabriva plans to file an NDA later this year. But Nabriva’s share price fell during the day, perhaps due to safety concerns about the first-in-class antibiotic.

woman in a laboratory microscope with microscope slide in hand.toned image.

In a stark example of a good news/bad news day, Nabriva Therapeutics PLC reported positive top-line data from a second Phase IIl trial for its novel antibiotic lefamulin in community-acquired bacterial pneumonia (CABP) on May 21, but by day’s end its share price tumbled after rising on the clinical data success earlier in the day.

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