J&J's Invokana Slows CKD Progression In Diabetes

Positive top-line efficacy data from the CREDENCE study suggest the SGLT2 inhibitor slows the progress of chronic kidney disease in type 2 diabetics, a finding which may eventually have a positive effect on the sales performance of the diabetic therapy.

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Johnson & Johnson may gain a useful marketing opportunity from becoming the first company in 15 years to show that one of its diabetes drugs, in this case the sodium-glucose co-transporter 2 (SGLT2) inhibitor, Invokana (canagliflozin), slows the progression of chronic kidney disease (CKD) in patients with type 2 diabetes.

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