The Israeli drug discovery and development company Compugen Inc. has joined forces with Bristol-Myers Squibb Co. to evaluate the safety and tolerability of Compugen’s COM701 in combination with BMS’s PD-1 inhibitor Opdivo (nivolumab) in patients with advanced solid tumors.
BMS, Compugen Pursue Multiple Checkpoint Inhibitions In Antibody Collaboration
Bristol-Myers Squibb is teaming up with Compugen to test the latter’s investigational antibody that targets a new checkpoint, PVRIG, in combination with its own antibody Opdivo. Combined inhibition of checkpoint mechanisms, such as PVRIG and TIGIT, is also on the cards for the future.
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