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Migraine Market Gets Competitive With Second, Third CGRP Inhibitor Launches

 
• By Mandy Jackson

CGRP inhibitors were a hot topic during third quarter earnings calls, with Amgen and Teva talking about reimbursement progress, while Lilly marked progress for its add-on treatment, Allergan calmed fears about Botox's migraine sales, and Alder said its intravenous drug is on track.

Migraine word written on wood block

The launch of the CGRP inhibitors marked the biggest shakeup in the migraine market since the triptans started going generic – and the sponsors were pushed during their third quarter earnings calls for details that can help clarify the competitive landscape.

Amgen Inc.'s and Novartis AG's Aimovig (erenumab), which the FDA approved in May, is the only CGRP inhibitor that's been on the market long enough to generate significant sales. Its $22m third quarter figure was notable since the company still is negotiating many of its contracts with payers and patients are receiving the subcutaneously administered biologic for free until their health plans or pharmacy benefit managers (PBMs) agree to cover the drug

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