Mersana Back On Track After Speedy Changes To ADC Program

Following a clinical hold for its lead product, Mersana explains how it re-engineered the program and how it is developing its ADC platform further.

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Mersana hurtled toward its clinical hold lift in 60 days • Source: Shutterstock

When Mersana Therapeutics Inc.'s Phase I program for its lead candidate XMT-1522, an antibody drug conjugate (ADC) targeting HER2, was put on partial clinical hold in July following a patient death, the company acted quickly to change the study protocols to regulator's satisfaction. (Also see "Mersana's ADC Technology Faces A Setback With Partial Clinical Trial Hold " - Scrip, 19 July, 2018.)

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