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Arena To Advance GI, Derm Ambitions With $800m From United For PAH Candidate

 
• By Joseph Haas

With $800m in upfront cash from United Therapeutics and $400m pegged to approvals for ralinepag, Arena gets capital for its R&D ambitions and a partner of choice to advance its Phase III PAH compound.

lung illustration

Arena Pharmaceuticals Inc. may have won on multiple fronts in its Nov. 15 licensing agreement with United Therapeutics Corp., conveying global rights to its Phase III pulmonary arterial hypertension (PAH) candidate in return for $800m up front and a pair of milestones that could bring in another $400m for US and international approvals of ralinepag.

Market analysts consistently expressed enthusiasm for the deal from Arena’s viewpoint, as it brings a substantial immediate return for a clinical asset, gives the San Diego biotech significant capital to advance two pipeline candidates moving toward late-stage development and places a PAH candidate with positive Phase II data in the hands of a company focused on that indication

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