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'Totality Of Data' Make A Case For Luspatercept In Beta-Thalassemia, MDS

 
• By Mandy Jackson

Acceleron/Celgene’s drug was effective across all endpoints in transfusion-dependent beta-thalassemia and myelodysplastic syndromes, but Acceleron CEO Habib Dable notes key secondary endpoints could be most meaningful to doctors treating these patients.

3-D Rendering Red Blood Cells

Luspatercept met the primary endpoints in its first two Phase III tests – in transfusion-dependent beta-thalassemia and myelodysplastic syndromes (MDS) in the BELIEVE and MEDALIST studies, respectively – but Acceleron Pharma Inc. CEO Habib Dable pointed to key secondary endpoints in both clinical trials that could be the most important data points to treating physicians.

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