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New Life For AstraZeneca’s SLE Treatment As Second Study Succeeds

 
• By Alexandra Shimmings

The second Phase III TULIP trial for AstraZeneca’s anifrolumab has succeeded where the first failed by hitting a new primary endpoint in systemic lupus erythematosus.

Tulip
TULIP may bud

New life has been breathed into AstraZeneca PLC’s potential treatment for systemic lupus erythematosus (SLE), anifrolumab, after a different primary endpoint was used in its second Phase III trial, TULIP 2. The program had looked in trouble after the first study, TULIP 1, which tested a different primary endpoint, failed a year ago.

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