Reata's Bardoxolone Promises Renal Benefits In Alport Syndrome

Another Positive Read-Out For A Clinical-Stage Reata Drug

Reata is moving ahead with commercial plans as its potential first-in-class Nrf2 activator, bardoxolone methyl, meets primary and secondary endpoints in a first-year interim analysis of the Phase III CARDINAL study in patients with Alport syndrome, an inherited form of chronic kidney disease (CKD).  

Kidneys
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For the second time in two months, Reata Pharmaceuticals Inc.. has reported positive clinical data for one of its product candidates, this time for another investigational product, bardoxolone methyl, in patients with Alport syndrome. This is the second most common inherited cause of renal failure after autosomal dominant polycystic kidney disease.

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