Sweden’s RhoVac Aims To Become An M&A Target

Late 2021 RV001 Phase IIb Data May Offer Trigger, CEO Says

RhoVac is in mid-stage trialing of a vaccine based on the RhoC protein that aids the metastatic potential of cancer cells and their ability to migrate and infiltrate other tissue. The Swedish biotech’s CEO believes the drug is a potential blockbuster.

Diagnosis
RhoVac's RV001 targets the RhoC protein which is indispensable for metastasis • Source: Shutterstock

A primary tumor rarely kills, but secondary tumors do and currently there is no therapy specifically designed to prevent early metastasis formation in prostate cancer. Swedish biotech RhoVac AB hopes its lead asset RV001, a vaccine that is in Phase IIb trials targeting the RhoC protein, will shortly offer such patients a drug that minimizes the risk of the cancer returning in metastatic form after curative intent treatment of the primary tumor, the biotech’s CEO told Scrip.

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