Roche Backs Blueprint's Precision Therapy Pralsetinib To Challenge Lilly

Paying $675m Upfront For Rights To RET Inhibitor

The collaboration between the Swiss major and Blueprint Medicines, which could be worth up to $1.7bn, should help pralsetinib provide stiff competition to Eli Lilly's RET mutation drug Retevmo.

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Roche looks a good fit for marketing pralsetinib • Source: Shutterstock

Roche Holding AG has delved deep into precision medicine again to license Blueprint Medicines Corporation's pralsetinib, a rearranged during transfection (RET) inhibitor that has been filed for lung and thyroid cancer and has shown potential as a rival for Eli Lilly and Company's recently approved same-class therapy Retevmo.

The Swiss drugmaker is paying $675m in cash and making a $100m equity investment in Blueprint for global co-development and commercialization rights (excluding Greater China where the licensee is CStone Pharmaceuticals Co. Ltd

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