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Lilly’s Mirikizumab Shows Superiority Vs. Cosentyx In Psoriasis

 
• By Joseph Haas

Lilly plans to file the anti-IL-23 antibody for approval in psoriasis based on two Phase III trials. The latest data head-to-head against IL-17 inhibitor Cosentyx may guide physicians on how to treat patients.

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Lilly's mirikizumab showed superiority versus Consentyx in three 52-week measures

Eli Lilly and Company is ready to file its interleukin-23 inhibitor mirikizumab with the US Food and Drug Administration for approval in moderate-to-severe plaque psoriasis after reporting results from a second successful Phase III study on 17 July. The OASIS-2 trial showed that the candidate was non-inferior to the interleukin-17 inhibitor Cosentyx (secukinumab) on three endpoints at 16 weeks and superior to Novartis AG’s market-leading biologic at 52 weeks on those same endpoints.

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Henlius In David Versus Goliath Race With Pfizer For First PD-L1 ADC

 
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AstraZeneca Logs Japan Growth Despite Price Cuts

 
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Camzyos nHCM Failure Could Open Door To Threat From Cytokinetics’ Aficamten

 
• By Alaric DeArment

BMS’s Phase III ODYSSEY-HCM study did not show statistical significance for either of its two primary endpoints.