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RNAi Partners Vie To Lead Race To Cure Hepatitis B

 
• By Joseph Haas

At EASL 2020, four partnerships updated RNA-interference or antisense efforts to reduce hep B surface antigen, believed to lead to functional cure of the virus. One analyst sees J&J/Arrowhead as the early leader.

Hepatitis B
Four partnerships are working toward HBV functional cure with RNAi/antisense technology

Four partnerships employing RNA-interference or antisense therapeutic approaches to treating hepatitis B reported data from mid-stage programs during the European Association for the Study of the Liver’s virtual conference held 27-29 August. It’s early in the race but Datamonitor Healthcare analyst Michael Haydock sees the Johnson & Johnson/Arrowhead Pharmaceuticals, Inc. partnership holding an early lead in potentially achieving a functional cure for the virus, pursued most closely by GlaxoSmithKline plc and Ionis Pharmaceuticals, Inc.

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