The European Commission has granted approval to Novartis’s novel cholesterol treatment inclisiran, under the brand name Leqvio.
EU First To Approve Novartis’s Cholesterol Drug Leqvio
Twice Yearly Dosing Is Key Selling Point
Novartis hopes its new RNAi-based therapy will be a blockbuster – but must eventually show it can cut heart attacks and cardiovascular deaths.

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The firm has lofty ambitions for the aldosterone synthase inhibitor to treat hypertension and kidney disease.
The ZENITH study is a landmark for Merck’s first-in-class activin signalling inhibitor and pulmonary arterial hypertension treatment.
The UK giant is forecasting peak sales of $5bn plus
The Belgian firm banks nearly €77.7m to push its Charcot-Marie-Tooth to proof-of-concept.
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The UK giant is forecasting peak sales of $5bn plus
Novo’s semaglutide has shown its benefits as an injectable in patients with peripheral arterial disease and as an oral agent in cardiovascular outcomes, but stronger results are expected soon from Lilly’s tirzepatide.
The small interference RNA therapeutic can be used by patients regardless of inhibitor status.