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Amgen Eschews Some Of Its BiTEs, But Otezla Spurs Growth

Pipeline Changes Planned As Data Evolved

 
• By Mandy Jackson

Without Otezla’s $2.2bn in 2020 sales, Amgen’s full-year revenue would have been slightly lower than in 2019, which is why all eyes are on the company’s R&D programs and near-term approvals.

Top view of calculator,keyboard,pen and notebook written with Fourth Quarter.
Amgen's 2020 revenue of $25.4bn was in line with consensus expectations • Source: Shutterstock

Amgen, Inc. has showcased its bispecific T-cell engager (BiTE) technology as a source of next-generation cancer therapies over the past few years, investing in the platform across a variety of hematological malignancies and tumor types, so it was surprising when the company revealed on 2 February in its fourth quarter 2020 earnings report that it has paused clinical trials and discontinued development for some of its BiTE candidates.

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