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Roche’s Tecentriq Glows In Pivotal Trial For Early Lung Cancer

Immunotherapy Improves DFS In Early NSCLC

 
• By Sten Stovall

Positive pivotal results with Tecentriq in early post-surgery lung cancer should give Roche’s PD-L1 inhibitor pole position within its class for the blockbuster indication. But rivals are hot on its tail.

IMPower010 Met Its Endpoint of Disease-Free Survival At Interim Analysis • Source: Shutterstock

Roche Holding AG’s Tecentriq (atezolizumab) looks likely to become the first programmed cell death protein-based therapy to be approved in early lung cancer after pivotal IMPower010 study showed that the PD-L1 inhibitor helped people with the condition live longer without their disease returning.

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New Data Strengthen Case For RemeGen’s Telitacicept In gMG

 
• By Dexter Jie Yan

Results from a China Phase III trial show the potential of RemeGen's fusion protein telitacicept in generalized myasthenia gravis. But study design differences make direct comparisons with argenx's FcRn inhibitor Vyvgart challenging.

UK Promises To ‘Turbo-Charge’ Clinical Trials As Tariff Threat Remains

 
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PureTech Weighs Up Pros And Cons Of Going Private

 
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Epsilogen Hits Antibody Acquisition Trail With TigaTx Takeover

 
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Following the near-total dominance of IgG antibodies, the UK group is backing the potential of IgA and IgE-based therapies to transform cancer treatment with the purchase of US-headquartered TigaTx.

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New Data Strengthen Case For RemeGen’s Telitacicept In gMG

 
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UK Promises To ‘Turbo-Charge’ Clinical Trials As Tariff Threat Remains

 
• By Andrew McConaghie

Faced with Trump’s hostile tariff moves, the UK aims to speed up clinical trial start times to support its pharma sector and invest £600m in a new health data research service.