TG Therapeutics Plans Cut-Price Challenger To Ocrevus In MS

Filing Expected In Q3

TG Therapeutics is confident its late-stage candidate can take a slice of the multiple sclerosis market away from Roche’s blockbuster.

Brain with MS
An MRI of the brain of an MS patient, yellow-gold-orange showing areas of demyelination. • Source: Alamy

Roche’s multiple sclerosis blockbuster Ocrevus looks set to face new competition from a rival CD20 targeting antibody from TG Therapeutics – who are willing to offer their drug at a significant discount, once approved.

More from Anticancer

More from Therapy Areas

GSK Ramps Up Neuroscience Investment With ABL Brain Shuttle Deal

 

The pact could be worth more than $2.6bn and adds to growing big pharma investment in the technology.

Epsilogen Hits Antibody Acquisition Trail With TigaTx Takeover

 
• By 

Following the near-total dominance of IgG antibodies, the UK group is backing the potential of IgA and IgE-based therapies to transform cancer treatment with the purchase of US-headquartered TigaTx.

Roche’s Brain Shuttle Delivers In Alzheimer’s, Moves Ahead To Phase III

 

By allowing it to enter the brain more easily, trontinemab’s brain shuttle brings more patients to ‘amyloid zero’ levels faster, and with fewer brain swelling side effects.