Bone Therapeutics SA may find itself with limited options for its lead product candidate, JTA-004, following the failure of its Phase III trial in knee osteoarthritis pain. Although a post-hoc analysis points to potential efficacy of JTA-004 in certain patients, the company is now focusing on ALLOB, which occupies the second place in its pipeline and is being developed for orthopedic indications.
Bone Has Tough Path Forward After Phase III Knee Osteoarthritis Fail
The company said the study of JTA-004 failed to meet its primary and key secondary endpoints, though a post-hoc analysis indicated activity in a patient subset.
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Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.
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