One of Ocular Therapeutics Inc.’s two Phase II candidates for dry eye disease – both reformulations of approved drugs administered via intracanicular insert – has failed to meet the primary endpoint in its latest trial readout. However, the Bedford, MA-based firm told Scrip on 22 October that OTX-CSI will not be removed from its research and development pipeline just yet.
Ocular’s Dry Eye Drug Fails In Phase II, But It Isn’t Giving Up Yet
Company hopes a different formulation of its intracanicular insert of cyclosporin might provide longer duration of drug in the eye and better tear production with it.
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Aldeyra’s dry eye candidate reproxalap received a second FDA complete response letter, but the firm expressed confidence about refiling quickly based on two ongoing studies.
Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.
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