As Novartis AG launches a strategic review of its ailing generics business Sandoz, the Swiss major has hiked peak sales targets for its two stellar commercial successes, Cosentyx and Entresto.
Unveiling Novartis's third quarter financials to journalists this morning, CEO Vas Narasimhan noted that sales of the cardiovascular therapy Entresto (sacubitril/valsartan) soared by 44% at constant currencies to $924m, "driven by demand as essential first-choice therapy for heart failure patients," according to the company. In the US, sales have been boosted by approval from the Food and Drug Administration in February of an expanded indication for heart failure for preserved ejection fraction (HFpEF) to add to Entresto's initial approval for heart failure with reduced ejection fraction (HFrEF)
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