Anyone expecting to see Novartis's Leqvio come flying out of the blocks got a dose of reality as the Swiss major gave an update on the launch of the closely watched cholesterol-lowering drug that revealed a stuttering start to a landmark population-based agreement in England.
In September last year, some 20 months after unveiling an alliance with NHS England to give at-risk patients speedy access to Leqvio (inclisiran), Novartis secured reimbursement in the country for the first-in-class small-interfering RNA (siRNA) drug that inhibits synthesis of PCSK9 which could be used to treat hundreds of thousands of cardiovascular patients
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