Akebia Therapeutics, Inc. and Otsuka Pharmaceutical Co. Ltd. have ended their collaboration for vadadustat, with the US originator regaining rights to the oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) in multiple international territories, including the US and Europe.
$55m For Akebia As Otsuka Confirms Vadadustat Exit
Japanese firm extricates itself from international deals for oral anemia drug, leaving Akebia potentially needing to find a new partner to progress development and commercialization.

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