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Pfizer Taps Into 'Doggybone DNA' For mRNA Vaccines, Gene Therapy Production

Targets Manufacturing Bottleneck

 
• By Andrew McConaghie

New enzyme-based approach could help make DNA-based therapy manufacturing faster, more scaleable and more reliable.

Pfizer
The deal allows Pfizer to manufacture 'doggybone DNA' in its own facilities, but further details have not been disclosed. • Source: Shutterstock

Pfizer has signed a deal with Touchlight to use its ‘doggybone DNA’ (dbDNA), a next-generation manufacturing platform for mRNA vaccines, therapeutics and gene therapies.

The London, UK-based company’s DNA manufacturing platform uses enzymes rather than the established E

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