Otsuka Pharmaceutical Co. Ltd. subsidiary Taiho Pharmaceutical Co. Ltd.’s newly approved FGFR inhibitor, Lytgobi (futibatinib), is going for a subset of a subset of patients with cholangiocarcinoma that represents a narrower population than its competitors, but could dominate that segment based on its better efficacy numbers. However, Relay Therapeutics, Inc.’s early-stage candidate, RLY-4008, has shown response rates that could pose an even greater competitive threat.
Taiho’s Lytgobi Faces Heavy Competition, But Sets Efficacy Bar For Now
The FGFR inhibitor beats prior entrants on efficacy in cholangiocarcinoma, although Relay presented data at ESMO for its investigational RLY-4008 showing especially high efficacy and tolerability.
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